This is an exciting time for physicists studying living systems because the toolkit for manipulating and measuring biological systems is beginning to allow us to work toward turning lists of parts and facts into general principles. Our laboratory uses theory and experiments to uncover such quantitative, mathematical laws and to search for new phenomena in systems of interacting genes and cells. The following are examples of research questions that we are currently interested in:
– What are the quantitative laws of ‘system failure’ in biology?
– How can fragility in biological systems be detected?
– What are the quantitative laws of decision-making?
The model organisms that we use are the yeast Saccharomyces cerevisiae and the nematode Caenorhabditis elegans.